Single Step ‘Cold’ Kit

The Galli® technology will bring about the first cGMP Gallium-68 “cold” kit which labels quantitatively at room temperature, yielding product at physiological pH, ready for QC and injection, in under a minute and in a single step directly from a Ga-68 generator to form a single isomeric species.

The ‘cold’ kit will enable clinics, not just hospitals, to administer the product, meaning a diagnosis can be carried out far more widely and conviently for both clinicians and patients.

It’s short manufacture time – 6 minutes to final product – ensures the tracer has greater activity compared to conventional ‘two-step’ kits and semi-automated synthesis modules, thus multiple doses can be obtained from a single elution of the generator.

If delivery to an off-site PET scanning facility is required, the single step kit enables a dose to be delivered further,

and it can still be delivered even as the generator ages, thus extending the useful lifetime of the generator.

THG-001 (Ga-68 THP-PSMA)

Our most advanced product to date, THG-001, aka Ga-68 THP-PSMA, utilizes the THP chelator at the centre of the the Galli® technology to image prostate cancer. THG-001 is currently recruiting for a Phase II clinical trial.

We are currently developing additional products across indications with both therapeutic and diagnostic applications.

Single step “cold” kit

The Galli® technology will bring about the first cGMP Gallium-68 “cold” kit which labels quantitatively at room temperature, yielding product at physiological pH, ready for QC and injection, in under a minute and in a single step directly from a Ga-68 generator to form a single isomeric species.

The ‘cold’ kit will enable clinics, not just hospitals, to administer the product, meaning a diagnosis can be carried out far more widely and conviently for both clinicians and patients.

It’s short manufacture time – 6 minutes to final product – ensures the tracer has greater activity compared to conventional ‘two-step’ kits and semi-automated synthesis modules,thus multiple doses can be obtained from a single elution of the generator.

If delivery to an off-site PET scanning facility is required, the single step kit enables a dose to be delivered further,

and it can still be delivered even as the generator ages, thus extending the useful lifetime of the generator.

THG-001 (Ga-68 THP-PSMA)

Our most advanced product to date, THG-001, aka Ga-68 THP-PSMA, utilizes the THP chelator at the centre of the the Galli® technology to image prostate cancer. THG-001 is currently recruiting for a Phase II clinical trial.

We are currently developing additional products across indications with both therapeutic and diagnostic applications.